These side effects may lead to falls which could cause bone fractures or other injuries. This risk is higher for people with conditions or other medications that could worsen these effects. If falls or any of these symptoms occur, contact your healthcare provider. Multiorgan hypersensitivity reactions drug reaction with eosinophilia and systemic symptoms [DRESS] : Potentially serious, sometimes fatal, multiorgan hypersensitivity reactions have been reported.
Tardive dyskinesia TD is a side effect that develops with prolonged use of antipsychotics. If you develop symptoms of TD, such as grimacing, sucking, and smacking of lips, or other movements that you cannot control, contact your healthcare provider immediately. All patients taking either first or second generation antipsychotics should have an Abnormal Involuntary Movement Scale AIMS completed regularly by their healthcare provider to monitor for TD. Second generation antipsychotics SGAs increase the risk of diabetes, weight gain, high cholesterol, and high triglycerides.
Olanzapine may lower your blood pressure. Medications used to lower blood pressure may increase this effect. This risk is increased when these medications are given as an injection. Cigarette and other types of smoke can decrease levels of olanzapine. Let your healthcare provider know if you start or stop smoking cigarettes. Nicotine patches do not impact olanzapine levels. It is very important to tell your doctor how you feel things are going during the first few weeks after you start taking olanzapine.
It will probably take several weeks to see big enough changes in your symptoms to decide if olanzapine is the right medication for you. Antipsychotic treatment is generally needed lifelong for persons with schizophrenia.
Your doctor can best discuss the duration of treatment you need based on your symptoms and illness. Last Updated: January This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication.
Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein. Search Close Menu.
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Advocacy Advocate for Change. Advocacy Policy Priorities. Advocacy Policy Platform. Advocacy Crisis Intervention. Advocacy State Fact Sheets. Store it at room temperature and away from excess heat and moisture not in the bathroom. Always store the orally disintegrating tablets in their sealed package, and use them immediately after opening the package. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to olanzapine. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Olanzapine pronounced as oh lan' za peen. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow? What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication? Brand names Brand names of combination products. Your doctor may start you on a low dose of olanzapine and gradually increase your dose.
Other uses for this medicine. What special precautions should I follow? Before taking olanzapine, tell your doctor and pharmacist if you are allergic to olanzapine or any other medications.
Be sure to mention any of the following: antidepressants; antihistamines; carbamazepine Tegretol ; dopamine agonists such as bromocriptine Parlodel , cabergoline Dostinex , levodopa Dopar, Larodopa , pergolide Permax , and ropinirole Requip ; fluoroquinolone antibiotics including ciprofloxacin Cipro , gatifloxacin Tequin not available in the United States , levofloxacin Levaquin , norfloxacin Noroxin , ofloxacin Floxin , others; fluvoxamine Luvox ; ipratropium Atrovent ; medications for anxiety, high blood pressure, irritable bowel disease, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems; omeprazole Prilosec ; rifampin Rifadin ; sedatives; sleeping pills; ticlopidine Ticlid ; and tranquilizers.
J Psychopharmacol Oxford. The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C. J Clin Invest. National Alliance on Mental Health. Olanzapine Zyprexa. Updated January An in vitro analysis of disintegration times of different formulations of olanzapine orodispersible tablet: A preliminary report. Drugs R D.
Olanzapine-induced weight gain in patients with bipolar i disorder: a meta-analysis. Published online November 10, Your Privacy Rights. To change or withdraw your consent choices for VerywellMind. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page. These choices will be signaled globally to our partners and will not affect browsing data. We and our partners process data to: Actively scan device characteristics for identification.
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